Lep-KO


Strain Information

Strain Name

SD-Lepem1Smoc

Cat. NO.

NR-KO-200001

Gene Symbol

Lep

Gene Synonyms

ob; obese

Human Ortholog

LEP

Ensembl ID

RGD ID

NCBI ID


Description

Using CRISPR/Cas9 technology, exon 2-3 of Lep gene was deleted to generate Lep knockout rat. 


Research application

Insulin resistance,obesity,and type 2 diabetes etc.

Status

Availability

Repository Live


Related Articles

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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