Abcb4-KO


Strain Information

Strain Name

SD-Abcb4em1Smoc

Cat. NO.

NR-KO-190006

Gene Symbol

Abcb4

Gene Synonyms

Mdr2, Pgy3

Human Ortholog

ABCB4

Ensembl ID

RGD ID

NCBI ID


Description

Using CRISPR/Cas9 technology, Abcb4-201 exon 1-28 and Abcb4-203 exon 1-28 of Abcb4 gene was deleted to generate Abcb4 knockout rat.

Research application

Energy-dependent efflux pump; may be involved in changes in bile formation in response to diabetes.

Status

Availability

Repository Live


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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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