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Acod1-CKO Mouse

Strain Name: C57BL/6-Acod1em1(flox)Smoc Mutation Type: Conditional Knockout Research Application:

These mice carry loxP sites flanking exon 2-4 of Acod1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Acod1 gene.

Appl1-CKO Mouse

Strain Name: B6.129-Appl1tm1(flox)Smoc Mutation Type: Conditional knockout Research Application:

These mice carry loxP sites flanking exon 5 of Appl1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of this gene.

Atl2-KO Mouse

Strain Name: C57BL/6-Atl2em1Smoc Mutation Type: Knockout Research Application:

Exon 2 of Atl2 gene was deleted to generate Atl2 knockout mice via CRISPR/Cas9 mediated recombination.

Degs2-KO Mouse

Strain Name: C57BL/6-Degs2em1Smoc Mutation Type: Knockout Research Application: Therapeutic antibody target

Using CRISPR/Cas9 technology, exon 2 of Degs2 gene was deleted to generate Degs2 knockout mice.

Igf2bp3-KO Mouse

Strain Name: C57BL/6-Igf2bp3em1Smoc Mutation Type: Knockout Research Application:

Using CRISPR/Cas9 technology, exon 4-5 of Igf2bp3 gene was deleted to generate Igf2bp3  knockout mice.

Il11-KO Mouse

Strain Name: C57BL/6-Il11em1Smoc Mutation Type: Knockout Research Application: Immune-related

This Il11 knockout mouse model was generated by knocking out the exon 2-4 region of the Il11 using CRISPR/Cas technology.

Kif3a-KO Mouse

Strain Name: C57BL/6-Kif3aem1Smoc Mutation Type: Knockout Research Application:

Exon 3 of Kif3a gene was deleted to generate Kif3a knockout mice via CRISPR/Cas9 mediated recombination.

Kir3dl2-KO Mouse

Strain Name: C57BL/6-Kir3dl2em1Smoc Mutation Type: Knockout Research Application: Therapeutic antibody target

Using CRISPR/Cas9 technology, exon 3-7 of Kir3dl2 gene was deleted to generate Kir3dl2 knockout mice.

R26-(SA-LSL-Notch1C-IRES-nEGFP) Mouse

Strain Name: C57BL/6-Gt(ROSA)26Sorem1(SA-LSL-Notch1C-IRES-nEGFP)Smoc Mutation Type: Knock-in Research Application: Spontaneous tumor model

These mice harbor a SA-LSL-Notch1C-IRES-nEGFP cassette in the Rosa26 locus generated by homologous recombination.Notch1C (mouse Notch1 ,amino acids 1749–2293)

Raf1-(D486N) Mouse

Strain Name: C57BL/6-Raf1em1(D486N)Smoc Mutation Type: Point mutaion Research Application: Noonan syndrome

These mice carry a p.D486N mutation of Raf1 gene.

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