Strain Name: C57BL/6J-Il11em1Smoc Mutation Type: Knockout Research Application: Immune-related
This Il11 knockout mouse model was generated by knocking out the exon 2-4 region of the Il11 using CRISPR/Cas technology.
Strain Name: B6.129-Appl1tm1(flox)Smoc Mutation Type: Conditional knockout Research Application:
These mice carry loxP sites flanking exon 5 of Appl1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of this gene.