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U-GEMMs

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Mice

hNECTIN4

Strain Name:C57BL/6Smoc-Nectin4tm1(hNECTIN4)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210016

The endogenous mice Nectin4 gene was replaced by human NECTIN4 gene.

Mice

hCXCR6

Strain Name:C57BL/6Smoc-Cxcr6em(hCXCR6)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215001

The endogenous mice Cxcr6 gene was replaced by human CXCR6 gene.

Mice

Il17a-Cre

Strain Name
Strain State:Repository Live | Cat. NO.:NM-KI-200137

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.

Mice

Karma-2A-tdTomato-2A-DTR

Strain Name:C57BL/6Smoc-Gpr141bem1(2A-tdTomato-2A-DTR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-210116

2A-tdTomato-2A-DTR expression cassette was knocked into the Karma gene.

Mice

R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190065

These mice harbor a CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Etv1-CreERT2

Strain Name:C57BL/6Smoc-Etv1em1(CreERT2-SV40-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200105

A CreERT2 expression cassette was knocked into the Etv1 gene start codon site. ETV1 expression is enriched in fast conduction tissues of embryonic and adult mammalian hearts. And ETV1 expression is upregulated in the atrial tissue of patients with permanent atrial fibrillation. Etv-CreERT2 mice can be applied to heart disease research. ETV1 is also expressed in retinal ganglion cells of adult mice, and the mouse model can be used to study how retinal ganglion cells contribute to visual processing in the brain.

Mice

Avil-Cre

Strain Name:C57BL/6Smoc-Avilem1(Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-215036

Cre expression cassette was knocked into the Avil gene.

Mice

Ifng-KO

Strain Name:C57BL/6Smoc-Ifngem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200723

Ifng-KO mice(Stock No.NM-KO-200723) carry a knockout allele derived from the targeted deletion of exon 1-4. While Ifng-KO(2) mice(Stock No.NM-KO-200873)carrying the exon 1 deletion.

Mice

Zap70-W163C(Balb/c)

Strain Name:BALB/cAnSmoc-Zap70em(W163C)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-210366

These mice carry a W163C mutation of Zap70 gene.

Mice

Trp63-CreERT2

Strain Name:C57BL/6Smoc-Trp63em(CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225021

A CreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene via CRISPR/Cas mediated recombination.

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