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U-GEMMs

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Mice

h4-1BBL

Strain Name:C57BL/6Smoc-Tnfsf9em1(hTNFSF9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00048

The endogenous mouse Tnfsf9 gene was replaced by human TNFSF9 gene.

Mice

hCD81

Strain Name:C57BL/6Smoc-Cd81em1(CD81)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190041

The endogenous mouse Cd81 gene was replaced by human CD81 gene.

Mice

hCD147

Strain Name:C57BL/6Smoc-Bsgtm1(hBSG)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000021

The endogenous mouse Bsg gene was replaced by human BSG gene.

Mice

R26-CAG-LSL-Luc-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-luci-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18051

A CAG-loxP STOP-loxP-luci-2A-tdTomato-WPRE-polyA cassette was knocked into the mouse ROSA26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that luciferase and tdTomato fluorescent protein could be expressed for cell tracing.

Mice

hDPP4

Strain Name:C57BL/6Smoc-Dpp4em1(DPP4)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190042

The endogenous mouse Dpp4 gene was replaced by human DPP4 gene.

Mice

Cd8a-IRES-DTRGFP/Cd8a-IRES-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Cd8aem2(IRES-DTREGFP)Cd8aem1(V5-IRES-luci-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-210399

Cd8a-IRES-DTRGFP(NM-KI-190045) was crossed with Cd8a-IRES-Luc-2A-EGFP(NM-KI-18030) to generate Cd8a-IRES-DTRGFP/Cd8a-IRES-luc-2A-EGFP mice.

Mice

hCD81/hOCLN

Strain Name:C57BL/6Smoc-Cd81em1(hCD81)Oclnem1(hOCLN)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000107

These mice are obtained through breeding of two single gene humanized mice.

Mice

hCTLA-4/Cd8a-IRES-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Ctla4em1(hCTLA4)Cd8aem1(V5-IRES-luc-2A-EGFP)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210374

hCTLA4(NM-HU-00014) was crossed with Cd8a-IRES-Akaluc-2A-EGFP(NM-KI-18030) to generate hCTLA4/Cd8a-IRES-Akaluc-2A-EGFP mice.

Mice

h4-1BB(2)/hPD-1

Strain Name:C57BL/6Smoc-Tnfrsf9tm2(h4-1BB)Pdcd1em1(hPDCD1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200279

h4-1BB(2)(NM-HU-190077) was crossed with hPD-1(NM-HU-00015)to generate h4-1BB(2)/hPD-1 mice

Mice

hCD47

Strain Name:C57BL/6Smoc-Cd47em1(hCD47)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00050

The endogenous mouse Cd47 gene was replaced by human CD47 gene.

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