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1190002N15Rik-CKO Mouse

Strain Name: B6.129-1190002N15Riktm1(flox)Smoc Mutation Type: Conditional knockout Research Application:

These mice possess loxP sites on either side of exon 2 and followed by an frt-neo-frt cassette. When crossed with a Cre recombinase-expressing strain,this strain is useful in eliminating tissue-specific conditional expression of the gene.

1300017j02Rik-KO Mouse

Strain Name: C57BL/6J-1300017j02Rikem1Smoc Mutation Type: Knockout Research Application: Immune-related

This 1300017j02Rik knockout mouse model was generated by knocking out the exon2-12 region of the 1300017j02Rik using CRISPR/Cas technology.

1700074P13Rik-KO Mouse

Strain Name: B6.129-1700074P13Riktm1Smoc Mutation Type: Knockout Research Application:

Exons 2-3 were replaced by pGK-Neo cassette.

1700121C10Rik-KO Mouse

Strain Name: C57BL/6J-1700121C10Rikem1smoc Mutation Type: Knockout Research Application: unknown

Using CRISPR/Cas9 technology, 1700121C10Rik gene was deleted to generate 1700121C10Rik knockout mice.

2310057M21Rik-KO Mouse

Strain Name: C57BL/6J-2310057M21Rikem1Smoc Mutation Type: Knockout Research Application: Immune-related

This 2310057M21Rik knockout mouse model was generated by knocking out the exon 2-3 region of the 2310057M21Rik using CRISPR/Cas technology.

4-1BB-HU Mouse

Strain Name: C57BL/6J-Tnfrsf9em1(hTNFRSF9) Smoc Mutation Type: Humanization Research Application: Immunotherapy,cancer research,drug screening

The endogenous mouse Tnfrsf9 gene was replaced by human TNFRSF9 gene  via CRISPR/Cas mediated recombination. Click here for detailed validation data. 

4-1BB-KO Mouse

Strain Name: C57BL/6J-Tnfrsf9em1Smoc Mutation Type: Knockout Research Application: Immune and hematopoietic research

Using CRISPR/Cas9 technology, gRNAs targeting exon2 of Tnfrsf9 (4-1BB) gene were used to generate Tnfrsf9 (4-1BB) knockout mice.

4-1BBL-HU Mouse

Strain Name: C57BL/6J-Tnfsf9em1(hTNFSF9)Smoc Mutation Type: Humanization Research Application: Immunotherapy,cancer research,drug screening

The endogenous mouse Tnfsf9 gene was replaced by human TNFSF9 gene via CRISPR/Cas mediated recombination.

4930578C19Rik-CKO Mouse

Strain Name: B6.129-4930578C19Riktm1(flox)Smoc Mutation Type: Conditional knockout Research Application:

These mice possess loxP sites on either side of exon 2 and followed by an frt-neo-frt cassette. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

9430015G10Rik-KO Mouse

Strain Name: C57BL/6J-9430015G10Rikem1Smoc Mutation Type: Knockout Research Application: Immune system, nervous system, pain

Using CRISPR/Cas9 technology,exon 4 of 9430015G10Rik gene was deleted to generate 9430015G10Rik knockout mice.

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