M-NSG

Nomenclature

NOD-Prkdcscid Il2rgem1/Smoc

Cat. NO.

NM-NSG-001

Strain State

Repository Live


Gene Summary

Official Symbol
Il2rg

Model Description

Prkdc and Il2rg genes were both knocked-out in NOD mice. 

  • Lacking mature T, B and NK cells
  • Low immune rejection against human cells and tissues
  • Good tumorigenicity so that a small number of cells can form tumors.
  • Significant improvement in the survival of transplanted human cells and tissues
  • Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models
  • Suitable as the carrier mice for the transplantation of heterologous cells and tissues
Research Application:Immune and hematopoietic research

Validation Data

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