R26-CAG-LSL-hEGFR*T790M/del19-Luc-tdTomato

Nomenclature

C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EGFR T790M-del19-luciferase-tdTomato)Smoc

Cat. NO.

NM-KI-190009

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Gt(ROSA)26Sor

Model Description

A SA-2xpolyA-CAG-LSL-EGFR(T790M-del19)-IRES-luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EGFR(T790M-del19) protein.
Research Application:cancer

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