hCD28(BALB/c,3)

Nomenclature

BALB/cAnSmoc-Cd28em(hCD28)Smoc

Cat. NO.

NM-HU-220509

Strain State

Repository Live

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Gene Summary

Gene Symbol
CD28

Model Description

The endogenous mouse Cd28 gene was replaced by human CD28 gene.


Validation Data

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Fig1. Detection of hCD28 expression on T cells in blood in hCD28(3) KI mice. 

(A) Human CD28 expression on CD4+ and CD8+ T cells in hCD28 mice; (B) Statistics of CD28+ cell populations in hCD28 mice.

image.png

Fig2. Detection of hCD28 expression on T cells in spleen in hCD28(3) KI mice. 

(A) Human CD28 expression on CD4+ and CD8+ T cells in hCD28 mice; (B) Statistics of CD28+ cell populations in hCD28 mice.

image.png

Fig3. Detection of hCD28 expression on T cells in thymus in hCD28(3) KI mice. 

(A) Human CD28 expression on CD4+ and CD8+ T cells in hCD28 mice; (B) Statistics of CD28+ cell populations in hCD28 mice.


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