P53-KO


Strain Information

Strain Name

B6.129-Trp53tm1Smoc

Cat. NO.

NM-KO-00011

Gene Symbol

Trp53

Gene Synonyms

bbl, bfy, bhy, p44, p53, Tp53

Human Ortholog

TRP53

Ensembl ID

MGI ID

NCBI ID


Description

A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high,early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts. Click here for details


Research application

Tumorigenesis,aging,antineoplastic drug evaluation etc

Status

Availability

Embryo cryopreservation


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