Wnt pathway is involved in pleomorphic adenomas induced by overexpression of PLAG1 in transgenic mice
Opposing functions of PLAG1 in pleomorphic adenoma:a microarray analysis of PLAG1 transgenic mice
Tumor-Initiating Cells Are Enriched in CD44hi Population in Murine Salivary Gland Tumor
The transgene of human PLAG1 cDNA expressed stably in tg mice which spontaneously developed salivary gland tumors. This tg mouse is a valued animal model for human salivary gland tumors.
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.查看