Il1b-(Luc-EGFP)


Strain Information

Strain Name

C57BL/6J-Il1bem1(Luc-eGFP)Smoc

Cat. NO.

NM-KI-00010

Gene Symbol

Il1b

Gene Synonyms

Il-1b, IL-1beta

Human Ortholog

IL1B

Ensembl ID

MGI ID

NCBI ID


Description

A Luciferase-2A-EGFP-pA cassette was inserted at ATG site of mouse Il1b gene via CRISPR/Cas mediated recombination. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1b.


Research application

Inflammation and immunity,gene tracing

Status

Availability

Embryo cryopreservation


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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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