Grid2-KO

Nomenclature

C57BL/6Smoc-Grid2em1Smoc

Cat. NO.

NM-KO-200981

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Grid2

Synonyms

Lc， ho， cpr， tpr， GluD2， Lc， Ms10ac， nmf408， MMS10-AC， GluRdelta2， B230104L07Rik

NCBI ID

14804

MGI ID

95813

Ensembl ID

ENSMUSG00000071424

Pubmed

Grid2

Human Ortholog

GRID2

Model Description

Exon 4 of Grid2 gene was deleted to generate Grid2 knockout mice.

Disease Connection

Autosomal Recessive Spinocerebellar Ataxia 18

Phenotype(s)

MGI:4949279

Reference(s)

Hills LB, Masri A, Konno K, Kakegawa W, Lam AT, Lim-Melia E, Chandy N, Hill RS, Partlow JN, Al-Saffar M, Nasir R, Stoler JM, Barkovich AJ, Watanabe M, Yuzaki M, Mochida GH, Deletions in GRID2 lead to a recessive syndrome of cerebellar ataxia and tonic upgaze in humans. Neurology. 2013 Oct 15;81(16):1378-86

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