FcRn-HU


Strain Information

Strain Name

C57BL/6J-Gt(ROSA)26Sorem1(CAG-hFcRn)Fcgrtem1/Smoc

Cat. NO.

NM-HU-00109

Gene Symbol

Fcgrt

Gene Synonyms

FcRn

Human Ortholog

FCGRT

Ensembl ID

MGI ID

NCBI ID


Description

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) knockin mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.


Research application

cancer research,Immunotherapy,drug screening

Status

Availability

Repository Live


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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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