Calb1-2A-GFPCre

Nomenclature

C57BL/6Smoc-Calb1em1(2A-EGFP-Cre)Smoc

Cat. NO.

NM-KI-200141

Strain State

Repository Live

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Gene Summary

Gene Symbol
Calb1

Synonyms

CB; Calb; Calb-1; Brain-2

NCBI ID

12307

MGI ID

88248

Ensembl ID

ENSMUSG00000028222

Pubmed

Calb1

Human Ortholog

CALB1

Model Description

A 2A-EGFP-Cre expression cassette was knocked into the Calb1 gene stop codon site. Calb1 is highly expressed in the brain. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful in studying many neurobehavioral diseases such as spatial learning and circadian rhythm interference. It has been reported that the incidence of many diseases may be different between genders.
Research Application：Cre recombinase tool

Validation Data

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Fig. 1 Cre-mediated recombination in the brain of Calb1GFPCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) and EGFP(green) expression can be detected in the cerebellar purkinje cells of Calb1GFPCre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) and EGFP(green) in various tissues of Calb1GFPCre/+; Rosa26tdTomato/+ mice. Tdtomato and EGFP expression can be detected in the brain, eyes, salivary gland, liver, kidney, pancreas, testis, epididymis, bronchi, brown fat, skin, stomach, heart, muscle, intestine and colon. (For more detailed information please contact our technical advisor.)


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