hICOSL(2)

Nomenclature

C57BL/6Smoc-Icosltm3(hICOSLG)/Smoc

Cat. NO.

NM-HU-2000068

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Icosl

Model Description

The endogenous mouse Icosl gene was replaced by human ICOSLG gene. While hICOSL(Stock No.NM-HU-00095) mice function similarly to hICOSL(2) mice,for more detailed information please contact our technical advisor.
Research Application:Immunotherapy,drug screening

Validation Data

NM-HU-2000068 hICOSLG.png

Fig1. Analysis of ICOSLG gene expression in the spleen by RT-PCR.

Mouse Icoslg mRNA was detectable by P1/2(276bp), human ICOSLG mRNA was detectable by P1/3(406bp), 

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human ICOSLG and mouse Icoslg in the spleen.


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