Apc-(L850X)


Strain Information

Strain Name

C57BL/6J-Apcem1(L850X)Smoc

Cat. NO.

NM-KI-200001

Gene Symbol

Apc

Gene Synonyms

CC1, Min, mAPC, AI047805, AU020952, AW124434

Human Ortholog

APC

Ensembl ID

MGI ID

NCBI ID


Description

These mice carry a p.L850X mutation of Apc gene.

Research application

Heterozygotes of this strain are highly susceptible to spontaneous intestinal adenoma formation. Homozygous mice are not viable.

Status

Availability

Repository Live


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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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