Dmd-KO

Nomenclature

C57BL/6Smoc-Dmdem3Smoc

Cat. NO.

NM-KO-200573

Strain State

Repository Live

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Gene Summary

Gene Symbol
Dmd

Synonyms

dys; mdx; pke; Dp71; Dp427; DXSmh7; DXSmh9

NCBI ID

13405

MGI ID

94909

Ensembl ID

ENSMUSG00000045103

Pubmed

Dmd

Human Ortholog

DMD

Model Description

Exon 52 of Dmd gene was deleted to generate Dmd knockout mice.
Research Application：Duchenne muscular dystrophy research

Disease Connection

Duchenne Muscular Dystrophy

Phenotype(s)

MGI:3573782

Reference(s)

Kudoh H, Ikeda H, Kakitani M, Ueda A, Hayasaka M, Tomizuka K, Hanaoka K, A new model mouse for Duchenne muscular dystrophy produced by 2.4Mb deletion of dystrophin gene using Cre-loxP recombination system. Biochem Biophys Res Commun. 2005 Mar 11;328(2):507-16

Validation Data

Dmd-ko.png

Fig1. DMD was not detected in heart tissue of the Dmd knockout mice by western blot.

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