Ctnnb1-KO


Strain Information

Strain Name

C57BL/6J-Ctnnb1em1Smoc

Cat. NO.

NM-KO-190634

Gene Symbol

Ctnnb1

Gene Synonyms

Bfc, Mesc, Catnb

Human Ortholog

CTNNB1

Ensembl ID

MGI ID

NCBI ID


Description

Using CRISPR/Cas9 technology,exon 3-6 of Ctnnb1 gene was deleted to generate Ctnnb1 knockout mice.

Research application

colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer

Status

Availability

Sperm cryopreservation


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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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