Brs3-KO


Strain Information

Strain Name

C57BL/6-Brs3em1Smoc

Cat. NO.

NM-KO-190608

Gene Symbol

Brs3

Gene Synonyms

BRS-3

Human Ortholog

BRS3

Ensembl ID

MGI ID

NCBI ID


Description

Using CRISPR/Cas9 technology,exon 2 of Brs3 gene was deleted to generate Brs3 knockout mice.

Research application

The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension.

Status

Availability

Embryo cryopreservation


Related Articles

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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