Npy5r-KO
Nomenclature
C57BL/6Smoc-Npy5Rem1Smoc
Cat. NO.
NM-KO-190602
Strain State
Developing
Gene Summary
Gene Symbol
Npy5r
Model Description
Exon 2 of Npy5r gene was deleted to generate Npy5r knockout mice.
Research Application：The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma.
*Literature published using this strain should indicate: Npy5r-KO mice (Cat. NO. NM-KO-190602) were purchased from Shanghai Model Organisms Center, Inc..
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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