Gabrr2-KO

Nomenclature

C57BL/6Smoc-Gabrr2em1Smoc

Cat. NO.

NM-KO-190581

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Gabrr2

Model Description

Exon 2 of Gabrr2 gene was deleted to generate Gabrr2 knockout mice.
Research Application:The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA type A receptor complex. This gene exists on chromosome 6q next to the gene encoding the rho 1 subunit of the GABA type A receptor, in a region thought to be associated with susceptibility for psychiatric disorders and epilepsy. Polymorphisms in this gene may also be associated with alcohol dependence, and general cognitive ability.

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