Agtr1a-KO


Strain Information

Strain Name

C57BL/6J-Agtr1Aem1Smoc

Cat. NO.

NM-KO-190909

Gene Symbol

Agtr1a

Gene Synonyms

AT1, AG2S, AT1a, AT2R1, Agtr1, AT2R1A, Agtr-1a, AI551199, Angtr-1a, 1810074K20Rik

Human Ortholog

Ensembl ID

MGI ID

NCBI ID


Description

Using CRISPR/Cas9 technology,exon 3 of Agtr1a gene was deleted to generate Agtr1a knockout mice.

Research application

Renal morphology and function, xenobiotic response, hyperreninemia, drinking behavior, angiotensin II-related vascular and hemodynamic responses

Status

Availability

Embryo cryopreservation*


Related Articles

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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