Cd74-KO
Nomenclature
C57BL/6Smoc-Cd74em1Smoc
Cat. NO.
NM-KO-190772
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Cd74
Model Description
Using CRISPR/Cas9 technology,exon 2 of Cd74 gene was deleted to generate Cd74 knockout mice.
Research Application：The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response.
*Literature published using this strain should indicate: Cd74-KO mice (Cat. NO. NM-KO-190772) were purchased from Shanghai Model Organisms Center, Inc..
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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