Cd2-KO


Strain Information

Strain Name

C57BL/6J-Cd2em1Smoc

Cat. NO.

NM-KO-191183

Gene Symbol

Cd2

Gene Synonyms

Ly37, LFA-2, Ly-37

Human Ortholog

CD2

Ensembl ID

MGI ID

NCBI ID


Description

Using CRISPR/Cas9 technology,exon 2-5 of Cd2 gene was deleted to generate Cd2 knockout mice.

Research application

The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition.

Status

Availability

Embryo cryopreservation


Related Articles

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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