Ccl11-KO


Strain Information

Strain Name

C57BL/6J-Ccl11em1Smoc

Cat. NO.

NM-KO-191181

Gene Symbol

Ccl11

Gene Synonyms

Scya11, eotaxin

Human Ortholog

CCL11

Ensembl ID

MGI ID

NCBI ID


Description

Using CRISPR/Cas9 technology,exon 2 of Ccl11 gene was deleted to generate Ccl11 knockout mice.

Research application

This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Status

Availability

Embryo cryopreservation


Related Articles

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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