Il27ra-KO

Nomenclature

C57BL/6Smoc-Il27raem1Smoc

Cat. NO.

NM-KO-190496

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Il27ra

Synonyms

CRL1， Tccr， Wsx1， WSX-1， IL-27R， zcytor1

NCBI ID

50931

MGI ID

1355318

Ensembl ID

ENSMUSG00000005465

Pubmed

Il27ra

Human Ortholog

IL27RA

Model Description

Exon 2-4 of Il27ra gene was deleted to generate Il27ra knockout mice.
Research Application：glycosylated transmembrane protein；Immune System

Disease Connection

Membranous Glomerulonephritis

Phenotype(s)

MGI:4943704
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Fas-KO(BALB/c)(NM-KO-191206) mice.

Reference(s)

Shimizu S, Sugiyama N, Masutani K, Sadanaga A, Miyazaki Y, Inoue Y, Akahoshi M, Katafuchi R, Hirakata H, Harada M, Hamano S, Nakashima H, Yoshida H, Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1). J Immunol. 2005 Dec 1;175(11):7185-92

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