Cela1-2A-DreERT2

Nomenclature

C57BL/6Smoc-Cela1em1(2A-DreERT2)Smoc

Cat. NO.

NM-KI-190094

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Cela1

Synonyms

Ela1; Ela-1; PC-TsF; 1810009A17Rik; 1810062B19Rik

NCBI ID

109901

MGI ID

95314

Ensembl ID

ENSMUSG00000023031

Pubmed

Cela1

Human Ortholog

CELA1

Model Description

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.
Research Application：Dre recombinase tool, pancreatic acinar cells

Validation Data

image.png

Fig.1 DreERT2-mediated recombination in the pancreas of Gja1DreERT2/+；R26tdTomato/+ mouse. TdTomato (red) expression can be detected in the pancreas after tamoxifen treatment. α-amylase(green) is a digestive enzyme that is predominantly secreted by the acinar cells of the exocrine pancreas. (Documented in the following reference.)


Publications

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

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