hIL2
Nomenclature
C57BL/6Smoc-Il2tm3(hIL2)Smoc
Cat. NO.
NM-HU-190048
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
IL2
Model Description
Validation Data
Fig1. Detection of IL2 expression by RT-PCR.
Wild type: only one band at 255 bp with primers F2/R2(mIl2); Homozygous: only one band at 320 bp with primers F1/R1(hIL2).
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Expression of human IL2 in the Serum of IL2-HU heterozygous mice is detected by ELISA.
Fig3. Expression of murine IL2 in the Serum of IL2-HU heterozygous mice and is detected by ELISA.
Fig4. Splenocytes from humanized IL2 mice were analyzed by flow cytometry after activation.
hIL2+ (but not mIL2+) cells were detectable in the homozygous hPD-L2 mice.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreOur vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more
