Dnmt1-CKO


Strain Information

Strain Name

C57BL/6-Dnmt1tm1(flox)Smoc

Cat. NO.

NM-CKO-190046

Gene Symbol

Dnmt1

Gene Synonyms

Dnmt, MCMT, Met1, Cxxc9, MTase, Met-1, Dnmt1o, m.MmuI, MommeD2

Human Ortholog

DNMT1

Ensembl ID

MGI ID

NCBI ID


Description

These mice carry loxP sites flanking exon9 of Dnmt1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dnmt1 gene.

Research application

Epigenetic

Status

Availability

Repository Live


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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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