Ccr2-KO

Nomenclature

C57BL/6Smoc-Ccr2em1Smoc

Cat. NO.

NM-KO-190018

Strain State

Repository Live

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Gene Summary

Gene Symbol
Ccr2

Model Description

This Ccr2 knockout mouse model was generated by knocking out the exon 3 region of the Ccr2 .
Research Application:Immune-related

Validation Data

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Fig1. Validation of Ccr2 gene expression by RT-PCR.(A) Schematic diagram of primer design; (B) No product was obtained from Ccr2 knockout homozygous mice, and the wild-type mice could obtain the 824bp target PCR product. (M, DNA marker; HO, homozygous; WT, wild type)


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Fig2. Validation of  CCR2 expression in the bone marrow by FACS. CCR2 expression could not be detected on CD11b+ cells of the Ccr2 knockout homozygous mice. 


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Fig3. Validation of CCR2 expression in the spleen by FACS. CCR2 expression could not be detected on CD11b+ cells of the Ccr2 knockout homozygous mice. 



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Milestones

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