Btk-KO


Strain Information

Strain Name

C57BL/6J-Btkem1Smoc

Cat. NO.

NM-KO-190005

Gene Symbol

Btk

Gene Synonyms

Bruton's tyrosine kinase, xid, X-linked immune deficiency

Human Ortholog

BTK

Ensembl ID

MGI ID

NCBI ID


Description

This Btk knockout mouse model was generated by knocking out the exon 4-5 region of the Btk using CRISPR/Cas technology.

Research application

Immune-related

Status

Availability

Embryo cryopreservation


Related Articles

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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