R26-(EZH2)


Strain Information

Strain Name

C57BL/6J-Gt(ROSA)26Sorem1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Smoc

Cat. NO.

NM-KI-18053

Gene Symbol

Gene Synonyms

Human Ortholog

EZH2

Ensembl ID

MGI ID

NCBI ID


Description

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus by CRISPR/Cas9 gene editing technology. This strain of mice can be mated with mice expressing  Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase.


Research application

Tumor research; drug screening

Status

Availability

Repository Live


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