Dgcr2-Hira-KO


Strain Information

Strain Name

C57BL/6J-Dgcr2em1Hiraem1Smoc

Cat. NO.

NM-KO-18060

Gene Symbol

Dgcr2,Hira

Gene Synonyms

9930034O06Rik, Dgcr2, Dgsc, DGS-C, Idd, Lan, Sez12,D16Ertd95e, Gm15797, Tuple1

Human Ortholog

DGCR2,HIRA

MGI ID

NCBI ID


Description

Using CRISPR/Cas9 technology, the sgRNAs were designed targeting Dgcr2 intron9 and Hira intron24 resulting in a sequence deletion of approximately 0.11 mb between the Dgcr2 gene and the Hira gene.

Research application

behavior, cardiovascular, mortality/aging, nervous system

Status

Availability

Repository Live


Related Articles

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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