Fcgr2b/Fcgr3/Fcgr4-KO


Strain Information

Strain Name

C57BL/6J-Fcgr2bem1Smoc Fcgr3em1Smoc Fcgr4em1Smoc

Cat. NO.

NM-KO-18037

Gene Symbol

Fcgr2b,Fcgr3,Fcgr4

Gene Synonyms

CD32, F630109E10Rik, FcgammaRIIB, Fc gamma RIIB, Fcgr2, Fcgr2a, FcgRII, Fc[g]RII, Fcr-2, Fcr-3, Ly-17, LyM-1, Ly-m20,CD16, FcgammaRIII, Fcg receptor III,4833442P21Rik, CD16-2, FcgammaRIV, Fcgr3a

Human Ortholog

FCGR2B,FCGR2A,FCGR3A

MGI ID

NCBI ID


Description

The Fcgr2b/Fcgr3/Fcgr4 triple knockout mouse model was obtained by knocking out all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene using CRISPR gene editing technology.


Research application

inflammation,autoimmunity

Status

Availability

Embryo cryopreservation


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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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