B2m-KO


Strain Information

Strain Name

NOD.Cg-PrkdcscidB2mem1Smoc

Cat. NO.

NM-KO-18035

Gene Symbol

B2m

Gene Synonyms

beta2-m, beta 2 microglobulin, Ly-m11

Human Ortholog

B2M

Ensembl ID

MGI ID

NCBI ID


Description

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of Nod-scid mice using CRISPR gene editing technology. This strain is an ideal model for xenograft transplantation studies and is an excellent source for insulitis-free, MHC class I-negative islets for transplantation studies.

Research application

immunodeficiency, immune system, transplantation research

Status

Availability

Repository Live


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Milestones

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