R26-e(CAG-LSL-KRAB-dCas9-IRES-EGFP)


Strain Information

Strain Name

C57BL/6J-Gt(ROSA)26Sorem1(CAG-LSL-KRAB-dCas9-IRES-EGFP)

Cat. NO.

NM-KI-18007

Gene Symbol

dCas9

Gene Synonyms

Human Ortholog

Ensembl ID

MGI ID

NCBI ID


Description

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via CRISPR/Cas mediated homologous recombination.  This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). Click here for details.


Research application

CRISPRi,gene regulation tool

Status

Availability

Repository Live


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Milestones

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