PD-1&PD-L1&OX40-HU


Strain Information

Strain Name

C57BL/6-Tnfrsf4em3(hTNFRSF4)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc

Cat. NO.

NM-HU-00122

Gene Symbol

Tnfrsf4,Pdcd1,Cd274

Gene Synonyms

Ox40, ACT35, CD134, Ly-70, Txgp1, TXGP1L,,PD-1, Pdc1, Ly101,Pdl1, Pdcd1l1, Pdcd1lg1, A530045L16Rik

Human Ortholog

TNFRSF4,PDCD1,CD274

MGI ID

NCBI ID


Description

This PD1 ,PD-L1 and OX40 triple knockin strain is established by crossing IDO1-HU, PD1-HU and CTLA4-HU mice of three humanized strains together. These triple double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.


Research application

Immunotherapy,cancer research,drug screening

Status

Availability

Repository Live


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The Company will be embarking on a brand upgrade project from April 2018 to better serve our clients. "南模生物 (Shanghai Model Organisms)" will be adopted as the Company's Chinese brand name, together with a new corporate logo. This will coincide with the launch of a new corporate website: www.modelorg.com.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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