OX40&CTLA4-HU


Strain Information

Strain Name

C57BL/6J-Tnfrsf4 em3(hTNFRSF4)  Ctla4em1(hCTLA4)/Smoc

Cat. NO.

NM-HU-00105

Gene Symbol

Tnfrsf4,Ctla4

Gene Synonyms

Ox40, ACT35, CD134, Ly-70, Txgp1, TXGP1L,Cd152, Ly-56, Ctla-4

Human Ortholog

TNFRSF4,CTLA4

MGI ID

NCBI ID


Description

These  mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.


Research application

Immunotherapy,cancer research,drug screening

Status

Availability

Repository Live


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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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