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In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9- activator transgenic mice

Model Organisms：Mice Product & Service：- Research field：Gene regulation

Published date：2018-01-15 | References：Nature Neuroscience

Downregulation of BDH2 modulates iron homeostasis and promotes DNA demethylation in CD4 + T cells of systemic lupus erythematosus

Model Organisms：Mouse Product & Service：Mir21a Research field：Immune system

Published date：2017-11-04 | References：CLIN IMMUNOL

Enhancing the precision of genetic lineage tracing using dual recombinases

Model Organisms：Mice Product & Service：IR1, IR2, NR1, NR2, CAG-DreER, Tnni3-Dre, Tnnt2-Dre, Alb-CreER, CK19-Dre 和 Alb-DreER Research field：Genetic lineage tracing

Published date：2017-11-01 | References：Nat Med

Electron leak from NDUFA13 within mitochondrial complex I attenuates ischemia-reperfusion injury via dimerized STAT3

Model Organisms：Mice Product & Service：NDUFA13 Research field：Heart

Published date：2017-11-01 | References：Proc Natl Acad Sci U S A

Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis

Model Organisms：Mice Product & Service：Stra8-GFPCre Research field：Reproductive system

Published date：2017-10-01 | References：Cell Res

PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum

Model Organisms：Mice Product & Service：Prrt2 Research field：Nervous System

Published date：2017-10-01 | References：Cell Res

Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium

Model Organisms：Mice Product & Service： Npr3-CreER、Wt1-CreER、Sox9-CreER 和 Nfatc1-2A-CreER Research field：Heart

Published date：2017-08-01 | References：Cell Res

MicroRNA-21 Is Required for Local and Remote Ischemic Preconditioning in Multiple Organ Protection Against Sepsis

Model Organisms：Mice Product & Service：miR-21 Research field：kidney

Published date：2017-07-01 | References：Crit Care Med

Knockout of the urate oxidase gene provides a stable mouse model of hyperuricemia associated with metabolic disorders

Model Organisms：Mice Product & Service：Uox Research field：kidney

Published date：2017-07-01 | References：Kidney Int

Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity

Model Organisms：Mice Product & Service：Setd2 Research field：Hepatitis B

Published date：2017-07-01 | References：Cell

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