IL-17D-induced inhibition of DDX5 expression in keratinocytes amplifies IL-36R-mediated skin inflammation

Model Organisms:Mice Product & Service:DDX5-flox, sIL36R-flox, K14-Cre Research field:atopic dermatitis and psoriasis

SEMA7AR148W mutation promotes lipid accumulation and NAFLD progression via increased localization on the hepatocyte surface

Model Organisms:Mice Product & Service:Sema7a -R148W Research field:NAFLD

T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies

Model Organisms:Mice Product & Service:M-NSG Research field:immune system,CAR-T

4-Phenylbutyrate restored γ-aminobutyric acid uptake and reduced seizures in SLC6A1 patient variant-bearing cell and mouse models

Model Organisms:Mice Product & Service:Slc6a1-S295L(NM-KI-190014) Research field:Rare disease

Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer

Model Organisms:Mice Product & Service:M-NSG Research field:Cancer

Advanced paternal age increased metabolic risks in mice offspring

Model Organisms:Mice Product & Service:HFD Research field:Metabolism

Dual Cre and Dre recombinases mediate synchronized lineage tracing and cell subset ablation in vivo.

Model Organisms:Mice Product & Service:R26-CAG-LSL-RSR-tdTomato-2A-DTR Research field:DTR mice

Incomplete lineage sorting and phenotypic evolution in marsupials

Model Organisms:Mice Product & Service:Wfikkn1-Q76R Research field:Developmental and Differentiation

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