Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL

Model Organisms:Mice Product & Service:Notch3-R170C Research field:CADASIL

Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain

Model Organisms:Mice Product & Service:R26-CAG-LSL-RSR-tdTomato-2A-DTR Research field:Obesity

Noncanonical contribution of microglial transcription factor NR4A1 to post-stroke recovery through TNF mRNA destabilization

Model Organisms:Mice Product & Service:Tmem119-2A-CreERT2 Research field:Microglia-mediated neuroinflammation, post-stroke recovery

Breaking Spatiotemporal Barriers of Immunogenic Chemotherapy via an Endoplasmic Reticulum Membrane-Assisted Liposomal Drug Delivery

Model Organisms:Mice Product & Service:huHSC-(M-NSG) Research field:antitumor immunity

IL-37 Attenuates Platelet Activation and Thrombosis Through IL-1R8 Pathway

Model Organisms:Mice Product & Service:Sigirr-flox Research field:coronary artery disease

Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy

Model Organisms:Mice Product & Service:Acod1-flox Research field:cancer immunotherapy

Ameliorating parkinsonian motor dysfunction by targeting histamine receptors in entopeduncular nucleus–thalamus circuitry

Model Organisms:Mice Product & Service:Slc17a6-IRES-Cre Research field:parkinsonian motor dysfunction

Maintaining hypoxia environment of subchondral bone alleviates osteoarthritis progression

Model Organisms:Mice Product & Service:LCP1-KO Research field:osteoarthritis

DNA repair mechanisms that promote insertion- deletion events during immunoglobulin gene diversification

Model Organisms:Mice Product & Service:Apex2-ko;Polh-ko Research field:immunoglobulin gene diversification

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