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Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL

Model Organisms：Mice Product & Service：Notch3-R170C Research field：CADASIL

Published date：2023-09-08 | References：Microbiome

Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain

Model Organisms：Mice Product & Service：R26-CAG-LSL-RSR-tdTomato-2A-DTR Research field：Obesity

Published date：2023-09-07 | References：Elseiver Sciense

Noncanonical contribution of microglial transcription factor NR4A1 to post-stroke recovery through TNF mRNA destabilization

Model Organisms：Mice Product & Service：Tmem119-2A-CreERT2 Research field：Microglia-mediated neuroinflammation, post-stroke recovery

Published date：2023-07-24 | References：

Breaking Spatiotemporal Barriers of Immunogenic Chemotherapy via an Endoplasmic Reticulum Membrane-Assisted Liposomal Drug Delivery

Model Organisms：Mice Product & Service：huHSC-(M-NSG) Research field：antitumor immunity

Published date：2023-06-13 | References：ACS Nano

A novel Anti-ROS osteoblast-specific delivery system for ankylosing spondylitis treatment via suppression of both inflammation and pathological new bone formation

Model Organisms：Mice Product & Service：Zap70-W163 Research field：Ankylosing Spondylitis

Published date：2023-05-26 | References：Journal of Nanobiotechnology

IL-37 Attenuates Platelet Activation and Thrombosis Through IL-1R8 Pathway

Model Organisms：Mice Product & Service：Sigirr-flox Research field：coronary artery disease

Published date：2023-04-28 | References：Circulation Research

Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy

Model Organisms：Mice Product & Service：Acod1-flox Research field：cancer immunotherapy

Published date：2023-04-28 | References：Science Advances

Ameliorating parkinsonian motor dysfunction by targeting histamine receptors in entopeduncular nucleus–thalamus circuitry

Model Organisms：Mice Product & Service：Slc17a6-IRES-Cre Research field：parkinsonian motor dysfunction

Published date：2023-04-25 | References：PNAS

Maintaining hypoxia environment of subchondral bone alleviates osteoarthritis progression

Model Organisms：Mice Product & Service：LCP1-KO Research field：osteoarthritis

Published date：2023-04-05 | References：Sciences Advances

DNA repair mechanisms that promote insertion- deletion events during immunoglobulin gene diversification

Model Organisms：Mice Product & Service：Apex2-ko;Polh-ko Research field：immunoglobulin gene diversification

Published date：2023-03-31 | References：SCIENCE IMMUNOLOGY

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