U-GEMMs

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

Mice
Strain Name:C57BL/6Smoc-Tg(hCEACAM5)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-TG-225005
Mice
Strain Name:C57BL/6Smoc-Tgtn(hCEACAM6)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-220288
Mice
Strain Name:C57BL/6Smoc-Tg(hCLDN18.2)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-220198
Mice
Strain Name:C57BL/6Smoc-Cldn6em1(hCLDN6)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225034
Mice
Strain Name:C57BL/6Smoc-Ddr1tm1(hDDR1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225086
Mice
Strain Name:C57BL/6Smoc-Dll3em1(hDLL3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200231
Mice
Strain Name:C57BL/6Smoc-Dll4tm1(hDLL4)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000020
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Egfrtm1(hEGFR)Smoc
Strain State:Developing | Cat. NO.:NM-HU-200227
Mice
Strain Name:C57BL/6Smoc-Engtm(hENG)Smoc
Strain State:Developing | Cat. NO.:NM-HU-220283
Mice
Strain Name:C57BL/6Smoc-EpCAMtm1(hEpCAM)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-210032
Research Application:inmmue therapy;drug screening
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