hB7H3

Nomenclature

C57BL/6Smoc-Cd276tm2(hB7H3)Smoc

Cat. NO.

NM-HU-00107

Strain State

Embryo cryopreservation

Export PDF

Gene Summary

Gene Symbol
CD276

Synonyms

B7H3; B7-h3; B7RP-2; AU016588; 6030411F23Rik

NCBI ID

102657

MGI ID

2183926

Ensembl ID

ENSMUSG00000035914

Pubmed

CD276

Human Ortholog

CD276

Model Description

The endogenous mouse Cd276 gene was replaced by human CD276 gene.
Research Application：cancer research,Immunotherapy,drug screening

Validation Data

image.png

Fig1.Detection of hB7H3 Expression in Blood-derived Macrophages and DCs in hB7H3 KI Mice

image.png

Fig2.Detection of hB7H3 Expression in Spleen-derived Macrophages and DCs in B7H3 KI Mice

image.png

Fig3.Detection of hB7H3 Expression in Bone Marrow-derived Macrophages and DCs in hB7H3 KI Mice

image.png

Fig4.hB7H3 Expression Cahraterization in Liver-derived Endothelial Cells (CD11b- CD31+) in hB7H3 KI Mice

image.png

Fig5.hB7H3 Expression Cahraterization in Lung-derived Endothelial Cells (CD45- CD31+) in hB7H3 KI Mice

image.png

Fig6.hB7H3 Expression Detection in Testis-derived Endothelial Cells (CD45- CD31+) in hB7H3 KI Mice

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more