U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000088
Research Application:Alzheimer's disease research
Mice
Strain Name:C57BL/6Smoc-Tnfsf13em(hTNFSF13)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220521
Mice
Strain Name:C57BL/6Smoc-Aqp4em1(hAQP4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210001
Research Application:drug screening
Mice
Strain Name:C57BL/6Smoc-Arem1(hAR)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225061
Mice
Strain Name:C57BL/6Smoc-Arih1em1(hARIH1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234704
Mice
Strain Name:C57BL/6Smoc-Asgr1em(hASGR1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230065
Mice
Strain Name:C57BL/6Smoc-Axltm1(hAXL)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215067
Mice
Strain Name:C57BL/6Smoc-B2mem(hB2M)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-230007
Mice
Strain Name:NOD-PrkdcscidIl2rgem1H2-D1em1(hB2M-HLA A2.1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-225089
Mice
Strain Name:NOD-PrkdcscidIl2rgem1B2mem1(hB2M-HLA A2.1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225090
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