U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Apoc3tm1(pAlb-hREN-WPRE-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-235088
Mice
Strain Name:C57BL/6Smoc-Avilem1(LSL-Kozak-hM3Dq-mCherry-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-232881
Mice
Strain Name:C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-200002
Research Application:corona virus related research
Mice
Strain Name:C57BL/6Smoc-Gnrhrem(hGNRHR-cDNA-WPRE-pA)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225091
Mice
Strain Name:C57BL/6Smoc-Igs2em1(CAG-LSL-ACHE-WPRE-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00067
Research Application:Cholinesterase related drug research
Mice
Strain Name:C57BL/6Smoc-Igs2em1(CAG-loxP-STOP-loxP-hHTTQ148-hHTT 3'UTR-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-234493
Mice
Strain Name:C57BL/6Smoc-Igs2em1(CAG-loxP-STOP-loxP-hLILRB4-IRES-EGFP-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-230387
Mice
Strain Name:C57BL/6Smoc-Igs2em1(CAG-LSL-PSEN1-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190110
Research Application:Alzheimer's research
Mice
Strain Name:C57BL/6Smoc-Igs2em1(CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-210145
Research Application:Cancer research
Mice
Strain Name:C57BL/6Smoc-Igs2em1(ALB promoter-human ALB-IRES-Luciferase-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200322
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