hBCMA

Nomenclature

C57BL/6Smoc-Tnfrsf17em1(hBCMA)Smoc

Cat. NO.

NM-HU-200228

Strain State

Repository Live

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Gene Summary

Gene Symbol
Tnfrsf17

Model Description

The endogenous mice Bcma gene was replaced by human BCMA gene.

Validation Data

image.png

Fig1. Detection of BCMA expression in large Intestine by RT-PCR. 

Wild type: only one band at 137 bp with primers F1/R1(mBcma);

Homozygous: only one band at 235 bp with primers F2/R2(hBCMA); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Expression characterization of hBCMA in spleen, small intestine and large intestine in homozygous hBCMA mice by western blot. 

Note: The anti-human BCMA antibody cross-reacted with mouse BCMA.


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