hCCR5

Nomenclature

C57BL/6Smoc-Ccr5tm1(hCCR5)/Smoc

Cat. NO.

NM-HU-2000065

Strain State

Embryo cryopreservation

Export PDF

Gene Summary

Gene Symbol
Ccr5

Model Description

The endogenous mouse Ccr5 gene was replaced by human CCR5 gene.
Research Application:Immunotherapy,drug screening

Validation Data

NM-HU-2000065 hCCR5.png

Fig1. Analysis of CCR5 gene expression in the spleen by RT-PCR.

Mouse Ccr5 mRNA was detectable by P1/2(869bp), human CCR5 mRNA was detectable by P1/3(607bp), 

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human CCR5 and mouse Ccr5 in the spleen.



You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more