U-GEMMs

Cytokine Receptors

SMOC has developed a set of mouse models expressing humanized cytokines receptors. These models are suitable to assess the efficacy of drugs targeting cytokines receptors in fully immunocompetent mice.

Mice
Strain Name:C57BL/6Smoc-Il2rbtm1(hIL2RB)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000055
Research Application:Cytokine humanization model;drug screening
Mice
Strain Name:C57BL/6Smoc-Il2rgem1(IL2RG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200007
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210354
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Il4ratm1(hIL4R)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190008
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Il6raem1(hIL6R)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00044
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Il7rtm1(hIL7R)Smoc
Strain State:Developing | Cat. NO.:NM-HU-210027
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Lair1tm1(hLILRA4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225074
Mice
Strain Name:C57BL/6Smoc-Tg(hLILRB1-hLILRB4)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-220022
Mice
Strain Name:C57BL/6Smoc-Lilrb4aem1(hLILRB4 )Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210024
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em2(hPD-L1)Ccr8em1(hCCR8)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210401
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