SMOC has developed a set of mouse models expressing humanized cytokines receptors. These models are suitable to assess the efficacy of drugs targeting cytokines receptors in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Il1raptm3(hIL1RAP)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000070
Research Application：Cytokine humanization model；drug screening
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Strain Name：C57BL/6Smoc-Il1rl1tm4(hIL1RL1)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000067
Research Application：Cytokine humanization model；drug screening
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Strain Name：C57BL/6Smoc-Il1rl2em1(hIL1RL2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215057
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Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210031
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Il2rgem1(IL2RG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220004
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Strain Name：C57BL/6Smoc-Il2ratm1(hIL2RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190064
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Il2ratm1(hIL2RA)Ccr8em1(hCCR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220096
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Strain Name：C57BL/6Smoc-Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210414
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Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220144
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Strain Name：C57BL/6Smoc-Il2rbtm1(hIL2RB)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000055
Research Application：Cytokine humanization model；drug screening
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