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A549Luc Cell

Disease:Carcinoma Organisms.:Human

F12 NUTRIENT MIX- KAIGHNS MOD(Invitrogen,21127022)+ 10%FBS

A549GFP Cell

Disease:Carcinoma Organisms.:Human

F12 NUTRIENT MIX- KAIGHNS MOD(Invitrogen,21127022)+ 10%FBS

A549mCherry Cell

Disease:Carcinoma Organisms.:Human

F12 NUTRIENT MIX- KAIGHNS MOD(Invitrogen,21127022)+ 10%FBS

M-NSG Severely Immunodeficient Mouse Article

Our own-developed M-NSG mice used the CRISPR/Cas9 technique to knock out both Prkdc and Il2rg genes from NOD mice to obtain severely immunodeficient mice. These mice lack mature T, B, and NK cells and are an important carrier for humanized mice, xenografts, and immune reconstitution. They also have significant values for the study on human hematopoietic stem cells, tumorigenesis and tumor treatment, immunodeficiency diseases, and immune mechanisms in the body.

Cancer Model Article

Undoubtedly, cancer research has risen to become the top priority in biomedicine. The mouse model plays an important role in the research on the genesis and development of tumor, as well as the research and development of cancer drugs. Animal cancer models allow researchers to evaluate the efficacy of anti-cancer immunotherapies. They also serve as screening models for anti-cancer drugs and support research on tumorigenesis and metastasis. Shanghai Model Organisms provides a variety of custom-engineered mouse cancer models to meet different research needs.

Mouse Models of Grafted/Induced Tumors Article

Shanghai Model Organisms can provide two types of tumor-bearing mouse models. One type is called cell-line-derived xenograft (CDX) model, which is derived by inoculating human or murine cell lines into immunodeficient mice, while the other type is called patient-derived xenograft (PDX) model, which is derived by inoculating tumor tissue blocks collected from patients into immunodeficient mice.

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